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Registered Nurse Travel Jobs in South Carolina

Top RN Travel Nurse Jobs in South Carolina

We currently offer 17 of the best RN travel jobs in South Carolina and 15 exclusive, high-paying Registered Nurse travel nurse jobs here that you won’t find anywhere else! RN travel jobs are currently available in cities like Hilton Head Island, Mount Pleasant and Rock Hill. We have new jobs updating daily, so be sure to Apply Now so our specialists can make sure you get first crack. We make it as easy as possible for you to compare RN nursing jobs by allowing you to filter based on traveling nurse salary, shift type, location or duration to find the right job for you.

The average Registered Nurse travel nurse working in South Carolina earned about $1,848 per week as of Mar 1, 2025. Today, you can find RN jobs with a salary range between $1,533 to $2,215 per week. The city with the highest paying RN job is currently Hilton Head Island with a position for a Registered Nurse – Progressive Care – PCU at $2,215 per week.

In South Carolina, there are a number of hospital facilities with RN nursing staff. Grand Strand Regional Medical Center in Myrtle Beach, Piedmont Medical Center in Rock Hill and East Cooper Medical Center in Mount Pleasant are well known in South Carolina.

If you have a specific start date in mind, the earliest start date in South Carolina is Mar 31, 2025 for a Registered Nurse – Progressive Care – PCU role at $2,215 per week. The latest start date for an RN job is Apr 28, 2025 for a Registered Nurse – Neonatal Intensive Care – NICU role at $1,963 per week. Find additional possibilities by sorting “start date” in the list below.

There are a variety of contract lengths available for a(n) RN travel job including 12 weeks and 13 weeks.

With great things to do, people to meet and places to see, South Carolina is a popular place for RN travel jobs! Also be sure to check out our resources on how to become a travel nurse and nursing license renewal.

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Top Cities in South Carolina with Travel Registered Nurse Jobs

AMN Healthcare currently has 17 travel Registered Nurse positions available in the state of South Carolina. Search the most recent jobs below, or click the button below to view all jobs.

View All Jobs in South Carolina

Highest Paying Jobs in Rock Hill, SC

AMN Healthcare currently has 9 travel Registered Nurse positions available in Rock Hill.
travel Exclusive Compact State
Registered Nurse – Intensive Care – ICU
  • Rock Hill, South Carolina – 29732
  • 12 D,
  • April 21, 2025
  • 13
$1,870 to $2,061
Weekly Pay*
Common Diagnosis/Treatment: Respiratory, Sepsis, DKA, GIB, general surgery, trauma, CT surgery, neuro/vascular sx, everything # of Beds: 16 Nurse Patient Ratio: 2/3:1 Charting: Cerner Scrub Color: Navy blue Areas of Float Support: traveler will float to 3 ICUs- ICU, MICU, CVICU but all within their scope (no CVICU patients). Special Procedures: CRRT, hypothermia protocol, balloon pump, impella, procedures at bedside
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travel Exclusive Compact State
Registered Nurse – Intensive Care – ICU
  • Rock Hill, South Carolina – 29732
  • 12 D,
  • April 21, 2025
  • 13
$1,870 to $2,061
Weekly Pay*
Common Diagnosis/Treatment: Respiratory, Sepsis, DKA, GIB, general surgery, trauma, CT surgery, neuro/vascular sx, everything # of Beds: 16 Nurse Patient Ratio: 2/3:1 Charting: Cerner Scrub Color: Navy blue Areas of Float Support: traveler will float to 3 ICUs- ICU, MICU, CVICU but all within their scope (no CVICU patients). Special Procedures: CRRT, hypothermia protocol, balloon pump, impella, procedures at bedside
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travel Exclusive Compact State
Registered Nurse – Telemetry
  • Rock Hill, South Carolina – 29732
  • 12 D,
  • April 21, 2025
  • 13
$1,657 to $1,826
Weekly Pay*
Common Diagnosis/Treatment: # of Beds: Nurse to Patient Ratio: Charting: Scrub Color: Areas of Float Support: Special Procedures:
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travel Exclusive Compact State
Registered Nurse – Progressive Care
  • Rock Hill, South Carolina – 29732
  • 12 D,
  • April 21, 2025
  • 13
$1,870 to $2,061
Weekly Pay*
Common Diagnosis/Treatment: sepsis, stroke, heart failure, PNA, respiratory failure, substance withdrawl, epilepsy, trauma, post op, MI, CAD, non-titratable cardiac drips, IV medications, Vital signs/nursing interventions q4 hours routinely, may be more f # of Beds: 51 Nurse Patient Ratio: 4-5:1 Charting: Cerner Scrub Color: Navy blue Areas of Float Support: intermediate and med/surg Special Procedures: chest tube insertion, PICC, central line insertion at bedside, dialysis patients, EMU monitoring.
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View all Jobs in Rock Hill

Highest Paying Jobs in Hilton Head Island, SC

AMN Healthcare currently has 3 travel Registered Nurse positions available in Hilton Head Island.
travel Exclusive Compact State
Registered Nurse – Progressive Care
  • Hilton Head Island, South Carolina – 29926
  • 12 N,
  • March 31, 2025
  • 13
$2,010 to $2,215
Weekly Pay*
Common Diagnosis/Treatment: CIWA, neuro, cardiac, pulmonary # of Beds: 34 Nurse to Patient Ratio: 5-6:1 Charting: Cerner Scrub Color: Areas of Float Support: float pool, ACU Special Procedures: n/a
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travel Exclusive Compact State
Registered Nurse – Neonatal Intensive Care
  • Hilton Head Island, South Carolina – 29926
  • 12 N,
  • April 28, 2025
  • 12
$1,781 to $1,963
Weekly Pay*
Common Diagnosis/Treatment: Post-Partum and GYN surgery # of Beds: 8 Nurse to Patient Ratio: 31:1 Charting: Cerner Scrub Color: Areas of Float Support: within skill set Special Procedures: none
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travel Exclusive Compact State
Registered Nurse – Progressive Care
  • Hilton Head Island, South Carolina – 29926
  • 12 N,
  • April 21, 2025
  • 13
$1,710 to $1,885
Weekly Pay*
HOSPITAL HOUSING OPTION!!! Common Diagnosis/Treatment: CIWA, neuro, cardiac, pulmonary # of Beds: 34 Nurse to Patient Ratio: 5-6:1 Charting: Cerner Scrub Color: Areas of Float Support: float pool, ACU Special Procedures: n/a
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View all Jobs in Hilton Head Island

Highest Paying Jobs in Mount Pleasant, SC

AMN Healthcare currently has 2 travel Registered Nurse positions available in Mount Pleasant.
travel Exclusive Compact State
Registered Nurse – Medical Surgical
  • Mount Pleasant, South Carolina – 29464
  • 12 N,
  • April 21, 2025
  • 13
$1,959 to $2,159
Weekly Pay*
Common Diagnosis/Treatment: orthopedic, spine, joint replacement; bariatric, urology, general surgery, colorectal, wound, vascular # of Beds: 28 plus 10 bed overflow Nurse to Patient Ratio: 5:1 days; 6:1 nights Charting: Cerner Scrub Color: navy blue Areas of Float Support: PCU and ICU – assignment to patient’s within MedSurg level I competency Special Procedures: none
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travel Exclusive Compact State
Registered Nurse – Medical Surgical
  • Mount Pleasant, South Carolina – 29464
  • 12 D,
  • April 21, 2025
  • 13
$1,959 to $2,159
Weekly Pay*
Common Diagnosis/Treatment: orthopedic, spine, joint replacement; bariatric, urology, general surgery, colorectal, wound, vascular # of Beds: 28 plus 10 bed overflow Nurse to Patient Ratio: 5:1 days; 6:1 nights Charting: Cerner Scrub Color: navy blue Areas of Float Support: PCU and ICU – assignment to patient’s within MedSurg level I competency Special Procedures: none
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View all Jobs in Mount Pleasant

Highest Paying Jobs in Fort Mill, SC

AMN Healthcare currently has 1 travel Registered Nurse positions available in Fort Mill.
travel Exclusive Compact State
Registered Nurse – Labor & Delivery
  • Fort Mill, South Carolina – 29715
  • 12 N,
  • April 21, 2025
  • 13
$1,533 to $1,690
Weekly Pay*
Piedmont Medical Center – Fort Mill is now open! The 100 bed facility will boast all-new equipment, high-level technology and a compassionate staff ready to meet your needs at every phase of life.
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View all Jobs in Fort Mill

Highest Paying Jobs in Summerville, SC

AMN Healthcare currently has 1 travel Registered Nurse positions available in Summerville.
travel Compact State
Registered Nurse – Pediatric Intensive Care – PICU
  • Summerville, South Carolina – 29485
  • 12 D,
  • April 14, 2025
  • 13
$1,662 to $1,832
Weekly Pay*
This position presents an opportunity to join an elite team of passionate physicians and nurses within the Pediatric Intensive Care Unit (PICU). You’ll find a challenging and rewarding environment where patient care is firmly rooted in compassion, innovation, and a drive for great outcomes. This highly esteemed facility welcomes creative, energetic caregivers.
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Discover Registered Nurse Jobs in South Carolina with AMN Passport!

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Statistics on RN Jobs in South Carolina

View helpful statistics about RN travel nursing jobs based on historical data in South Carolina. This data is based on the last three months of RN job postings. Our statistics are updated regularly, which means you can find the most accurate Registered Nurse job salary trends, the types of shifts, and common contract durations available and more. Learn more about travel nursing salaries.

Salary Range

Salary Trends

Jobs by Facility types

FAQs about Registered Nurse Jobs in South Carolina

On average, how much does an RN travel nurse make in South Carolina?

A Registered Nurse nurse in South Carolina can make an average of $1,808 per week.

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How much does a night shift RN travel nurse make on average in South Carolina?

A: A 12 Hour Night shift Registered Nurse in South Carolina can make an average of $1,784 per week based on recent job availability.

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How much does a day shift RN make on average in South Carolina?

A: A 12 Hour Day shift Registered Nurse in South Carolina can make an average of $1,802 per week based on recent job availability.

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How many travel Registered Nurse jobs are currently available in South Carolina?

There are currently 17 Registered Nurse travel nursing jobs available in South Carolina. We also get new jobs daily, so be sure to apply now and a recruiter will help you find the perfect fit as jobs become available.

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Historically, what hospitals and healthcare facilities have Registered Nurse staff in South Carolina?

  • Dental Access Carolina, LLC in Rock Hill
  • MUSC Health Kershaw Medical Center in Camden
  • Grand Strand Surgical Care in Myrtle Beach
  • Complete Dental Care of Easley in Easley
  • MUSC Health Shawn Jenkins Childrens Hospital (FKA MUSC Childrens Hospital) in Charleston
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How long is the most common RN travel nursing contract in South Carolina?

12 Hour Night shifts was the most common duration for an RN traveling nurse job in South Carolina cities based on the last 6 months.

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How long is the most common contract duration for RN travel jobs in South Carolina?

13 weeks is the most common duration for a(n) Registered Nurse travel job in South Carolina based on recent data.

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What are the top paying RN jobs available in South Carolina currently?

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Locating RN Travel Nursing Jobs in South Carolina

Cities like Hilton Head, Mount Pleasant, Myrtle Beach, Rock Hill, and Summerville currently have RN travel jobs. It’s a great state to work in and is home to facilities like Dental Access Carolina, LLC, MUSC Health Kershaw Medical Center, Grand Strand Surgical Care, Complete Dental Care of Easley and MUSC Health Shawn Jenkins Childrens Hospital (FKA MUSC Childrens Hospital) which all have RN departments.

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Healthcare Facilities in South Carolina that offer Registered Nurse Jobs

These are just examples of some of the healthcare facilities in and around the South Carolina area that have historically offered jobs for Registered Nurse professionals.

McLeod Regional Medical Center
Shifts
8 D, 10 D, 12 D, 12 E, and 12 N
Job Durations
12, 1, 13, and 14
Departments
Cardiovascular Operating Room Cardiovascular Operating Room Cardiovascular Operating Room Cath Lab Emergency Room First Assist Medical Surgical Operating Room Operating Room Outpatient Clinic Progressive Care Unit
Address
555 E Cheves St
Florence, SC 29506
Nearby Neighborhoods
Wilson Heights (29502), Woodmont (29502), Wilson Estates (29502), Ponderosa (29501), Williams Heights (29502)
Piedmont Medical Center
Shifts
10 D, 12 D, 12 E, and 12 N
Job Durations
12, 13, and 8
Departments
Cardiovascular ICU Emergency Room Intensive Care Unit Labor & Delivery Medical Surgical Neonatal Intensive Care Unit Operating Room Progressive Care Unit Telemetry
Address
222 South Herlong Ave
Rock Hill, SC 29732
Nearby Neighborhoods
Botany Woods (29732), Greenfield Acres (29732), Old Farm (29732), Heatherwood (29732), Westerwood Acres (29732)
Hilton Head Hospital
Shifts
8 D, 10 D, 12 D, 12 E, and 12 N
Job Durations
12, 13, 118, 6, and 11
Departments
Cardiovascular Operating Room Cath Lab Emergency Room Emergency Room Intensive Care Unit Labor & Delivery Labor & Delivery Medical Surgical Neonatal Intensive Care Unit Operating Room Operating Room Operating Room Post Anesthesia Care Unit Post Anesthesia Care Unit Postpartum Progressive Care Unit Progressive Care Unit
Address
25 Hospital Center Blvd
Hilton Head Island, SC 29926
Trident Medical Center
Shifts
8 D, 10 D, 12 D, and 12 N
Job Durations
13, 8, and 26
Departments
Cardiovascular Operating Room Cardiovascular Operating Room Case Manager Cath Lab Dialysis Intensive Care Unit Interventional Radiology Operating Room Psychiatric Rehabilitation
Address
9330 Medical Plaza Dr
Charleston, SC 29406
Nearby Neighborhoods
Huntington Woods (29407), Parkshire (29405), Sandhurst (29407), Plantation Estates (29407), North Pine Point (29407)
East Cooper Medical Center
Shifts
10 D, 12 D, and 12 N
Job Durations
12, 1, 13, and 14
Departments
Medical Surgical Operating Room Postpartum Progressive Care Unit
Address
2000 Hospital Dr
Mount Pleasant, SC 29464
Nearby Neighborhoods
Parish Place (29465), Point Pleasant (29465), Wando Estates (29413), Somerset Point (29413), Hickory Shadows (29465)
Grand Strand Regional Medical Center
Shifts
8 D, 10 D, 12 D, 12 E, and 12 N
Job Durations
16 and 13
Departments
Cardiovascular Operating Room Case Manager Cath Lab Operating Room Pediatric Intensive Care Unit Rehabilitation
Address
809 82nd Parkway
Myrtle Beach, SC 29572
Nearby Neighborhoods
Northwood (29572), The Dunes (29572), Long Bay (29572), Oakland Heights (29572), Cane Patch (29572)
McLeod Health Cheraw (FKA: Chesterfield General Hospital)
Shifts
8 D, 10 D, and 12 D
Job Durations
13
Departments
Medical Surgical Operating Room
Address
711 CHESTERFIELD HWY.
Cheraw, SC 29520
Bon Secours St. Francis Downtown (Simplify)
Shifts
10 D, 12 D, and 12 N
Job Durations
12 and 13
Departments
Cardiovascular ICU First Assist Operating Room
Address
1 Saint Francis Dr
Greenville, SC 29601
Nearby Neighborhoods
University Ridge Homes (29601), Boyce Lawn (29616), Mountain View Homes (29601), Alta Vista (29603), Roosevelt Heights (29603)
* Estimate of payments is intended for informational purposes and includes hourly wages, as well as reimbursements for meal & incidental expenses and housing expenses incurred on behalf of the Company. Please speak with a recruiter for additional details.